I made a trainer on my licensed game from Origin. For the trainer to work, the game process must be called ME2Game.
If you have a pirated version, in which the game process is called MassEffect2, then you will not be able to activate the trainer and half of the functions will not work.
Mass Effect 2: Trainer (+17) [1.2.1604.0 Origin] {Ded_Mazay1991} Free Download
Trust me I checked!